CMap Candidate Details

Structure:
CMap ID: C10441
Pert ID: BRD-K25412176
Compound Name: GSK-2110183
Targets: --
MoA: --
SMILES: Cn1ncc(Cl)c1-c1cc(sc1Cl)C(=O)N[C@H](CN)Cc1cccc(F)c1
InchiKey: AFJRDFWMXUECEW-LBPRGKRZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
38 BRD-K25412176 BJAB 10 uM 4 h 0.2 0.85 0.0 0.25 0.89 0.2
75 BRD-K25412176 HBL1 10 uM 24 h 0.25 1.04 0.15 -0.35 -1.17 1.13
117 BRD-K25412176 K562 10 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.5
158 BRD-K25412176 KMS34 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
201 BRD-K25412176 NALM6 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
240 BRD-K25412176 OCILY10 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
301 BRD-K25412176 OCILY19 10 uM 4 h 0.25 1.03 0.14 -0.28 -0.93 0.35
319 BRD-K25412176 OCILY3 10 uM 24 h -0.27 -1.13 0.4 -0.25 -0.85 0.19
357 BRD-K25412176 SKMEL5 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
413 BRD-K25412176 THP1 2.5 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
454 BRD-K25412176 TMD8 10 uM 4 h 0.25 1.03 0.13 0.0 0.0 0.0
95852 BRD-K25412176 NPC 2.5 uM 6 h 0.0 0.0 0.0 -0.38 -1.28 1.45
95912 BRD-K25412176 YAPC 2.5 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95951 BRD-K25412176 A549 2.5 uM 6 h -0.25 -1.06 0.25 0.0 0.0 0.0
121883 BRD-K25412176 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121931 BRD-K25412176 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121997 BRD-K25412176 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122030 BRD-K25412176 HUVEC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122098 BRD-K25412176 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.17
122130 BRD-K25412176 MDAMB231 10 uM 24 h 0.2 0.86 0.01 0.33 1.18 0.98
130248 BRD-K25412176 HEK293 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130276 BRD-K25412176 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130332 BRD-K25412176 JURKAT 0.74 uM 24 h 0.16 0.67 0.0 0.22 0.78 0.07
130385 BRD-K25412176 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130471 BRD-K25412176 PC3 2.22 uM 24 h -0.24 -0.99 0.13 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).