CMap Candidate Details

Structure:
CMap ID: C01048
Pert ID: BRD-A42649439
Compound Name: triciribine
Targets: AKT3; AKT1; AKT2
MoA: Akt inhibitor
SMILES: Cn1nc(N)c2cn(C3OC(CO)C(O)C3O)c4ncnc1c24
InchiKey: HOGVTUZUJGHKPL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2806 BRD-A42649439 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3316 BRD-A42649439 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3584 BRD-A42649439 PC3 10 uM 6 h 0.18 0.75 0.0 -0.42 -1.4 2.02
3685 BRD-A42649439 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39045 BRD-A42649439 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39272 BRD-A42649439 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39567 BRD-A42649439 ASC 10 uM 24 h -0.27 -1.11 0.38 0.0 0.0 0.0
39893 BRD-A42649439 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40176 BRD-A42649439 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40425 BRD-A42649439 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40695 BRD-A42649439 NEU 10 uM 24 h 0.2 0.82 0.0 -0.34 -1.15 1.07
40993 BRD-A42649439 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41317 BRD-A42649439 SKB 10 uM 24 h 0.3 1.25 0.56 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).