CMap Candidate Details

Structure:
CMap ID: C01049
Pert ID: BRD-A42699921
Compound Name: teriflunomide
Targets: DHODH
MoA: Dihydroorotate dehydrogenase inhibitor
SMILES: CC(=O)C(C#N)C(=O)Nc1ccc(cc1)C(F)(F)F
InchiKey: NABQBYDEMLGCEO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
87992 BRD-A42699921 A549 3.33 uM 24 h 0.0 0.0 0.0 -0.37 -1.26 1.35
88035 BRD-A42699921 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121579 BRD-A42699921 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121625 BRD-A42699921 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121694 BRD-A42699921 YAPC 10 uM 24 h 0.25 1.02 0.13 -0.32 -1.07 0.77
129574 BRD-A42699921 A375 0.74 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.72
129621 BRD-A42699921 HT29 0.03 uM 24 h 0.16 0.65 0.0 0.3 1.06 0.58
129673 BRD-A42699921 PC3 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).