CMap Candidate Details

Structure:
CMap ID: C10492
Pert ID: BRD-K25591257
Compound Name: resveratrol
Targets: SIRT1; PTGS1; PTGS2
MoA: SIRT activator; Cytochrome P450 inhibitor
SMILES: Oc1ccc(C=Cc2cc(O)cc(O)c2)cc1
InchiKey: LUKBXSAWLPMMSZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1567 BRD-K25591257 HA1E 10 uM 24 h 0.22 0.9 0.02 0.22 0.76 0.05
2094 BRD-K25591257 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2231 BRD-K25591257 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2548 BRD-K25591257 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41749 BRD-K25591257 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42080 BRD-K25591257 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42334 BRD-K25591257 ASC 10 uM 24 h 0.0 0.0 0.0 0.32 1.12 0.77
42659 BRD-K25591257 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42964 BRD-K25591257 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43306 BRD-K25591257 MCF??7.00 10 uM 6 h -0.23 -0.96 0.09 0.0 0.0 0.0
43526 BRD-K25591257 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43824 BRD-K25591257 PHH 10 uM 24 h -0.25 -1.03 0.2 0.25 0.87 0.18
44094 BRD-K25591257 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).