CMap Candidate Details

Structure:
CMap ID: C10501
Pert ID: BRD-K25630527
Compound Name: LY-2784544
Targets: --
MoA: --
SMILES: Cc1cc(Nc2cc(CN3CCOCC3)c3nc(C)c(Cc4ccc(Cl)cc4F)n3n2)[nH]n1
InchiKey: SQSZANZGUXWJEA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95673 BRD-K25630527 U2OS 1.11 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
120893 BRD-K25630527 A549 3.33 uM 24 h 0.24 0.98 0.09 0.42 1.49 2.26
120920 BRD-K25630527 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120970 BRD-K25630527 HEK293 10 uM 24 h -0.24 -1.01 0.17 0.0 0.0 0.0
121057 BRD-K25630527 MCF??7.00 10 uM 24 h 0.23 0.95 0.07 -0.27 -0.91 0.3
121127 BRD-K25630527 YAPC 10 uM 24 h -0.2 -0.85 0.01 -0.35 -1.17 1.14
129102 BRD-K25630527 A375 2.22 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
129171 BRD-K25630527 HELA 2.22 uM 3 h 0.24 0.99 0.1 0.0 0.0 0.0
129203 BRD-K25630527 HT29 2.22 uM 24 h -0.33 -1.38 1.08 0.0 0.0 0.0
129229 BRD-K25630527 PC3 2.22 uM 24 h 0.0 0.0 0.0 -0.38 -1.29 1.53
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).