CMap Candidate Details

Structure:
CMap ID: C10539
Pert ID: BRD-K25737009
Compound Name: CD-1530
Targets: RARG
MoA: Retinoid receptor agonist
SMILES: OC(=O)c1ccc(cc1)c2ccc3cc(c(O)cc3c2)C4(CC5CC6CC(C5)C4)C6
InchiKey: YSGDXEKQTNMRQN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9391 BRD-K25737009 AGS 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10487 BRD-K25737009 HCT116 40 uM 6 h 0.29 1.22 0.47 -0.26 -0.88 0.25
11063 BRD-K25737009 HT29 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11453 BRD-K25737009 NCIH2073 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12018 BRD-K25737009 NCIH596 40 uM 6 h 0.0 0.0 0.0 -0.47 -1.57 15.65
12765 BRD-K25737009 SW480 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12954 BRD-K25737009 THP1 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13462 BRD-K25737009 VCAP 40 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.78
97830 BRD-K25737009 MCF??7.00 3.33 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
118406 BRD-K25737009 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118440 BRD-K25737009 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118474 BRD-K25737009 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118517 BRD-K25737009 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.42 -1.42 2.12
118561 BRD-K25737009 HEPG2 10 uM 24 h 0.0 0.0 0.0 -0.41 -1.38 2.02
118667 BRD-K25737009 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119761 BRD-K25737009 JURKAT 10 uM 24 h -0.2 -0.85 0.01 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).