CMap Candidate Details

Structure:
CMap ID: C01057
Pert ID: BRD-A43082555
Compound Name: loxoprofen
Targets: --
MoA: --
SMILES: CC(C(O)=O)c1ccc(CC2CCCC2=O)cc1
InchiKey: YMBXTVYHTMGZDW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25295 BRD-A43082555 VCAP 10 uM 24 h 0.0 0.0 0.0 0.34 1.19 1.03
123280 BRD-A43082555 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123375 BRD-A43082555 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123436 BRD-A43082555 PC3 0.04 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.6
123507 BRD-A43082555 YAPC 3.33 uM 24 h -0.22 -0.94 0.07 -0.32 -1.08 0.79
131533 BRD-A43082555 A375 0.08 uM 24 h 0.19 0.79 0.0 0.34 1.22 1.15
131562 BRD-A43082555 A549 2.22 uM 24 h 0.2 0.85 0.01 -0.24 -0.81 0.14
131642 BRD-A43082555 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131670 BRD-A43082555 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131692 BRD-A43082555 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131798 BRD-A43082555 JURKAT 0.08 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.21
131871 BRD-A43082555 MCF??7.00 0.03 uM 24 h 0.21 0.88 0.01 -0.25 -0.85 0.2
131903 BRD-A43082555 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131940 BRD-A43082555 THP1 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).