CMap Candidate Details

Structure:
CMap ID: C10583
Pert ID: BRD-K25875056
Compound Name: SC-9
Targets: PRKCA
MoA: Protein tyrosine kinase activator
SMILES: Clc1cccc2c(cccc12)S(=O)(=O)NCCCCCCc1ccccc1
InchiKey: YUXMTDYHFPRPLG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4085 BRD-K25875056 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4397 BRD-K25875056 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
4791 BRD-K25875056 PC3 10 uM 6 h 0.25 1.06 0.19 0.0 0.0 0.0
5059 BRD-K25875056 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39106 BRD-K25875056 A375 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.21 1.24
39435 BRD-K25875056 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39653 BRD-K25875056 ASC 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.14
39969 BRD-K25875056 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40246 BRD-K25875056 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40458 BRD-K25875056 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
41075 BRD-K25875056 NPC 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
41407 BRD-K25875056 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).