CMap Candidate Details

Structure:
CMap ID: C10620
Pert ID: BRD-K25991148
Compound Name: warfarin
Targets: VKORC1
MoA: Vitamin K antagonist
SMILES: CC(=O)C[C@@H](c1ccccc1)c1c(O)c2ccccc2oc1=O
InchiKey: PJVWKTKQMONHTI-HNNXBMFYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33613 BRD-K25991148 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34071 BRD-K25991148 ASC 10 uM 24 h -0.24 -0.99 0.14 0.33 1.16 0.9
34337 BRD-K25991148 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.83 0.16
34587 BRD-K25991148 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34857 BRD-K25991148 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35119 BRD-K25991148 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35418 BRD-K25991148 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35553 BRD-K25991148 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35756 BRD-K25991148 NPC 10 uM 24 h -0.28 -1.17 0.49 -0.3 -1.02 0.6
35945 BRD-K25991148 PC3 10 uM 24 h 0.0 0.0 0.0 0.21 0.73 0.03
36233 BRD-K25991148 PHH 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
36527 BRD-K25991148 SKB 10 uM 24 h -0.27 -1.13 0.41 -0.34 -1.15 1.07
36796 BRD-K25991148 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96125 BRD-K25991148 A549 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.79
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).