CMap Candidate Details

Structure:
CMap ID: C10631
Pert ID: BRD-K26015241
Compound Name: ODQ
Targets: GUCY1A2
MoA: Guanylyl cyclase inhibitor
SMILES: O=c1onc2cnc3ccccc3n12
InchiKey: LZMHWZHOZLVYDL-UHFFFAOYSA-N
Compound Aliases: odq

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1568 BRD-K26015241 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
2095 BRD-K26015241 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.58
2386 BRD-K26015241 PC3 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.86 0.21
2471 BRD-K26015241 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41750 BRD-K26015241 A375 10 uM 6 h 0.17 0.69 0.0 -0.3 -1.01 0.56
41923 BRD-K26015241 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42660 BRD-K26015241 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42965 BRD-K26015241 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43307 BRD-K26015241 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.81
43527 BRD-K26015241 NPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.88
43825 BRD-K26015241 PHH 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.57
44095 BRD-K26015241 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).