CMap Candidate Details

Structure:
CMap ID: C10735
Pert ID: BRD-K26341917
Compound Name: L-ergothioneine
Targets: --
MoA: --
SMILES: C[N+](C)(C)[C@@H](Cc1c[nH]c(=S)[nH]1)C(O)=O
InchiKey: SSISHJJTAXXQAX-ZETCQYMHSA-O
Compound Aliases: l-ergothioneine

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90957 BRD-K26341917 HUH7 15 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
120897 BRD-K26341917 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120923 BRD-K26341917 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120978 BRD-K26341917 HEK293 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121061 BRD-K26341917 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121135 BRD-K26341917 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129105 BRD-K26341917 A375 0.03 uM 24 h 0.0 0.0 0.0 0.34 1.19 1.05
129156 BRD-K26341917 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.36 1.26 1.29
129208 BRD-K26341917 HT29 0.74 uM 24 h -0.23 -0.97 0.11 0.4 1.42 2.2
129236 BRD-K26341917 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.37 1.3 1.49
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).