CMap Candidate Details

Structure:
CMap ID: C01074
Pert ID: BRD-A43671941
Compound Name: oxprenolol
Targets: ADRB1
MoA: Adrenergic receptor antagonist
SMILES: CC(C)NCC(O)COc1ccccc1OCC=C
InchiKey: CEMAWMOMDPGJMB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6838 BRD-A43671941 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6930 BRD-A43671941 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7391 BRD-A43671941 HA1E 10 uM 6 h 0.24 1.0 0.1 0.3 1.06 0.6
7536 BRD-A43671941 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7948 BRD-A43671941 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8445 BRD-A43671941 PC3 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.8 0.12
8756 BRD-A43671941 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
52093 BRD-A43671941 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).