CMap Candidate Details

Structure:
CMap ID: C10783
Pert ID: BRD-K26521938
Compound Name: dinoprostone
Targets: PTGER1; PTGER2; PTGER3; PTGER4
MoA: Prostanoid receptor agonist
SMILES: CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CC=C/CCCC(O)=O
InchiKey: XEYBRNLFEZDVAW-ARSRFYASSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1570 BRD-K26521938 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2097 BRD-K26521938 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2301 BRD-K26521938 PC3 10 uM 24 h -0.19 -0.79 0.0 0.0 0.0 0.0
2789 BRD-K26521938 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.28 1.45
42082 BRD-K26521938 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42336 BRD-K26521938 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42662 BRD-K26521938 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.28 0.99 0.39
42967 BRD-K26521938 HT29 10 uM 6 h 0.0 0.0 0.0 0.31 1.1 0.7
43176 BRD-K26521938 MCF??7.00 10 uM 24 h -0.29 -1.22 0.61 0.0 0.0 0.0
43827 BRD-K26521938 PHH 10 uM 24 h -0.26 -1.09 0.32 0.24 0.84 0.12
44097 BRD-K26521938 SKB 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.35 2.01
90966 BRD-K26521938 HUH7 10 uM 72 h -0.24 -1.0 0.15 0.0 0.0 0.0
98801 BRD-K26521938 NPC 10 uM 6 h 0.25 1.05 0.17 0.0 0.0 0.0
98876 BRD-K26521938 NEU 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.11
99782 BRD-K26521938 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).