CMap Candidate Details

Structure:
CMap ID: C10799
Pert ID: BRD-K26573499
Compound Name: DMAB-anabaseine
Targets: CHRNA7
MoA: Adrenergic receptor agonist
SMILES: CN(C)c1ccc(cc1)C=C1CCCN=C/1c1cccnc1
InchiKey: KHUUTHZSRXABAC-DTQAZKPQSA-N
Compound Aliases: dmab-anabaseine

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1571 BRD-K26573499 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.3 1.58
2098 BRD-K26573499 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2387 BRD-K26573499 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41752 BRD-K26573499 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42083 BRD-K26573499 A549 10 uM 6 h -0.32 -1.34 0.97 0.0 0.0 0.0
42337 BRD-K26573499 ASC 10 uM 24 h -0.31 -1.29 0.78 -0.3 -1.0 0.53
42663 BRD-K26573499 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42968 BRD-K26573499 HT29 10 uM 6 h 0.0 0.0 0.0 0.2 0.72 0.02
43309 BRD-K26573499 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43529 BRD-K26573499 NPC 10 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
44098 BRD-K26573499 SKB 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.34 1.85
90302 BRD-K26573499 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99783 BRD-K26573499 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).