CMap Candidate Details

Structure:
CMap ID: C01081
Pert ID: BRD-A43930669
Compound Name: L-368899
Targets: OXTR
MoA: Oxytocin receptor antagonist
SMILES: Cc1ccccc1N1CCN(CC1)S(=O)(=O)CC12CCC(C[C@@H]1NC(=O)[C@@H](N)CCS(C)(=O)=O)C2(C)C
InchiKey: MWIASLNTAGRGGA-WVJGRJQASA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1496 BRD-A43930669 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
1825 BRD-A43930669 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2263 BRD-A43930669 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2601 BRD-A43930669 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41669 BRD-A43930669 A375 10 uM 6 h 0.0 0.0 0.0 0.28 1.0 0.43
41883 BRD-A43930669 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42206 BRD-A43930669 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42550 BRD-A43930669 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42857 BRD-A43930669 HT29 10 uM 6 h 0.0 0.0 0.0 0.26 0.94 0.28
43262 BRD-A43930669 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.93 0.35
43407 BRD-A43930669 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44007 BRD-A43930669 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).