CMap Candidate Details

Structure:
CMap ID: C10828
Pert ID: BRD-K26657438
Compound Name: imiquimod
Targets: TLR7; TLR8
MoA: TLR agonist; Interferon inducer
SMILES: CC(C)Cn1cnc2c(N)nc3ccccc3c12
InchiKey: DOUYETYNHWVLEO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9191 BRD-K26657438 A549 10 uM 6 h 0.32 1.34 0.89 -0.27 -0.92 0.33
9392 BRD-K26657438 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9703 BRD-K26657438 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9948 BRD-K26657438 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10202 BRD-K26657438 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.32
11454 BRD-K26657438 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11739 BRD-K26657438 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12293 BRD-K26657438 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13245 BRD-K26657438 U937 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.81
13463 BRD-K26657438 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91433 BRD-K26657438 HUH7 15 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
98877 BRD-K26657438 NEU 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.05
99134 BRD-K26657438 NPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
117331 BRD-K26657438 A375 1.11 uM 24 h -0.23 -0.97 0.11 -0.33 -1.1 0.86
117500 BRD-K26657438 HEPG2 0.125 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
117544 BRD-K26657438 HT29 1.11 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
117587 BRD-K26657438 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120068 BRD-K26657438 HELA 10 uM 3 h 0.0 0.0 0.0 0.33 1.18 0.98
128842 BRD-K26657438 PC3 2.22 uM 24 h -0.18 -0.75 0.0 0.0 0.0 0.0
128861 BRD-K26657438 YAPC 0.74 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).