CMap Candidate Details

Structure:
CMap ID: C01083
Pert ID: BRD-A43974499
Compound Name: reboxetine
Targets: SLC6A2
MoA: Adrenergic receptor antagonist
SMILES: CCOc1ccccc1OC(C2CNCCO2)c3ccccc3
InchiKey: CBQGYUDMJHNJBX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1497 BRD-A43974499 HA1E 10 uM 24 h 0.17 0.69 0.0 0.0 0.0 0.0
2039 BRD-A43974499 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.97 0.46
2264 BRD-A43974499 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2603 BRD-A43974499 VCAP 10 uM 24 h 0.0 0.0 0.0 0.21 0.74 0.04
41670 BRD-A43974499 A375 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.77 0.08
42012 BRD-A43974499 A549 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
42207 BRD-A43974499 ASC 10 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.23
42551 BRD-A43974499 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42858 BRD-A43974499 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43126 BRD-A43974499 MCF??7.00 10 uM 24 h 0.31 1.29 0.64 0.0 0.0 0.0
43408 BRD-A43974499 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44008 BRD-A43974499 SKB 10 uM 24 h 0.27 1.13 0.28 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).