CMap Candidate Details

Structure:
CMap ID: C01086
Pert ID: BRD-A44008656
Compound Name: doxylamine
Targets: HRH1
MoA: Histamine receptor antagonist
SMILES: CN(C)CCOC(C)(c1ccccc1)c1ccccn1
InchiKey: HCFDWZZGGLSKEP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5520 BRD-A44008656 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6134 BRD-A44008656 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24385 BRD-A44008656 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24723 BRD-A44008656 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24844 BRD-A44008656 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24988 BRD-A44008656 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25473 BRD-A44008656 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42208 BRD-A44008656 ASC 10 uM 24 h -0.19 -0.81 0.0 0.0 0.0 0.0
43409 BRD-A44008656 NPC 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.11
44009 BRD-A44008656 SKB 10 uM 24 h 0.0 0.0 0.0 0.32 1.12 0.77
52653 BRD-A44008656 A549 0.08 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
52703 BRD-A44008656 HEPG2 20 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).