CMap Candidate Details

Structure:
CMap ID: C01090
Pert ID: BRD-A44133049
Compound Name: azasetron
Targets: HTR3A
MoA: Serotonin receptor antagonist
SMILES: CN1C(=O)COc2c1cc(Cl)cc2C(=O)NC1CN2CCC1CC2
InchiKey: WUKZPHOXUVCQOR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2040 BRD-A44133049 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
2265 BRD-A44133049 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2742 BRD-A44133049 VCAP 10 uM 6 h 0.0 0.0 0.0 0.37 1.32 1.6
24386 BRD-A44133049 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24724 BRD-A44133049 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.93 0.35
25068 BRD-A44133049 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41884 BRD-A44133049 A549 10 uM 24 h 0.28 1.16 0.35 0.0 0.0 0.0
42209 BRD-A44133049 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42552 BRD-A44133049 HEPG2 10 uM 6 h -0.18 -0.75 0.0 0.0 0.0 0.0
42859 BRD-A44133049 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43410 BRD-A44133049 NPC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.14
43720 BRD-A44133049 PHH 10 uM 24 h 0.0 0.0 0.0 0.21 0.74 0.03
44010 BRD-A44133049 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).