CMap Candidate Details

Structure:
CMap ID: C01095
Pert ID: BRD-A44448661
Compound Name: pentobarbital
Targets: GABRA1; GABRA2; GABRA3; GABRA4; GABRA5; GABRA6; GABRB1; GABRB2; GABRB3; GABRD; GABRE; GABRG1; GABRG2; GABRG3; GABRP; GABRQ
MoA: GABA receptor modulator; Barbiturate antiepileptic
SMILES: CCCC(C)C1(CC)C(=O)NC(=O)NC1=O
InchiKey: WEXRUCMBJFQVBZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6933 BRD-A44448661 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7539 BRD-A44448661 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7949 BRD-A44448661 HT29 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.05 0.69
8580 BRD-A44448661 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121551 BRD-A44448661 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121588 BRD-A44448661 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121630 BRD-A44448661 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121672 BRD-A44448661 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121698 BRD-A44448661 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129679 BRD-A44448661 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).