CMap Candidate Details

Structure:
CMap ID: C10972
Pert ID: BRD-K27141178
Compound Name: SB-203186
Targets: HTR4
MoA: Serotonin receptor antagonist
SMILES: O=C(OCCN1CCCCC1)c1c[nH]c2ccccc12
InchiKey: YGKPIROTKVQCCU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6735 BRD-K27141178 A375 10 uM 24 h -0.17 -0.69 0.0 0.32 1.14 0.87
7147 BRD-K27141178 A549 10 uM 6 h -0.21 -0.86 0.01 0.35 1.23 1.21
7434 BRD-K27141178 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7640 BRD-K27141178 HCC515 10 uM 6 h 0.21 0.86 0.01 -0.3 -1.0 0.54
7852 BRD-K27141178 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8084 BRD-K27141178 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8358 BRD-K27141178 PC3 10 uM 24 h 0.19 0.78 0.0 0.0 0.0 0.0
8659 BRD-K27141178 VCAP 10 uM 24 h 0.28 1.17 0.36 -0.26 -0.87 0.23
99788 BRD-K27141178 U2OS 10 uM 6 h 0.0 0.0 0.0 0.27 0.95 0.32
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).