CMap Candidate Details

Structure:
CMap ID: C10990
Pert ID: BRD-K27184429
Compound Name: levocetirizine
Targets: HRH1
MoA: Histamine receptor antagonist
SMILES: OC(=O)COCCN1CCN(CC1)[C@H](c1ccccc1)c1ccc(Cl)cc1
InchiKey: ZKLPARSLTMPFCP-OAQYLSRUSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25498 BRD-K27184429 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
120896 BRD-K27184429 A549 0.04 uM 24 h -0.2 -0.85 0.01 0.25 0.88 0.18
120922 BRD-K27184429 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120977 BRD-K27184429 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121006 BRD-K27184429 HELA 10 uM 3 h 0.0 0.0 0.0 -0.38 -1.28 1.45
121060 BRD-K27184429 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121134 BRD-K27184429 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129104 BRD-K27184429 A375 2.22 uM 24 h 0.22 0.92 0.04 0.26 0.92 0.24
129207 BRD-K27184429 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129235 BRD-K27184429 PC3 0.01 uM 24 h 0.34 1.41 1.03 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).