CMap Candidate Details

Structure:
CMap ID: C00011
Pert ID: BRD-A00376169
Compound Name: KBG
Targets: MME
MoA: Neprilysin inhibitor
SMILES: OC1O[C@@H]2COC(O[C@H]2[C@H](O)[C@H]1O)c1ccccc1
InchiKey: FOLRUCXBTYDAQK-SFZUHQLGSA-N
Compound Aliases: kbg

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122876 BRD-A00376169 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122960 BRD-A00376169 HT29 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123001 BRD-A00376169 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123052 BRD-A00376169 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 -0.35 -1.2 1.16
123090 BRD-A00376169 MDAMB231 0.37 uM 24 h 0.28 1.19 0.41 -0.22 -0.73 0.04
123142 BRD-A00376169 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123162 BRD-A00376169 THP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131199 BRD-A00376169 A375 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131228 BRD-A00376169 A549 0.01 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
131269 BRD-A00376169 HA1E 0.08 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.68
131297 BRD-A00376169 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.28 1.01 0.44
131338 BRD-A00376169 HUVEC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131423 BRD-A00376169 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131481 BRD-A00376169 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).