CMap Candidate Details

Structure:
CMap ID: C01101
Pert ID: BRD-A44863528
Compound Name: proglumide
Targets: CCKAR; CCKBR
MoA: CCK receptor antagonist
SMILES: CCCN(CCC)C(=O)C(CCC(O)=O)NC(=O)c1ccccc1
InchiKey: DGMKFQYCZXERLX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125229 BRD-A44863528 A375 0.04 uM 24 h -0.3 -1.25 0.7 0.0 0.0 0.0
125252 BRD-A44863528 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125291 BRD-A44863528 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125344 BRD-A44863528 HELA 0.37 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
125366 BRD-A44863528 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125388 BRD-A44863528 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 -0.38 -1.29 1.53
125427 BRD-A44863528 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125482 BRD-A44863528 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125511 BRD-A44863528 THP1 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125538 BRD-A44863528 YAPC 0.04 uM 24 h 0.19 0.77 0.0 0.0 0.0 0.0
133379 BRD-A44863528 HA1E 0.74 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 0.99
133502 BRD-A44863528 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133536 BRD-A44863528 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).