CMap Candidate Details

Structure:
CMap ID: C11041
Pert ID: BRD-K27351809
Compound Name: nomegestrol-acetate
Targets: PGR
MoA: Progesterone receptor agonist
SMILES: CC(=O)O[C@@]1(CC[C@H]2[C@@H]3C=C(C)C4=CC(=O)CC[C@@H]4[C@H]3CC[C@]12C)C(C)=O
InchiKey: IIVBFTNIGYRNQY-YQLZSBIMSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2859 BRD-K27351809 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3170 BRD-K27351809 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3609 BRD-K27351809 PC3 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.49
3763 BRD-K27351809 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44353 BRD-K27351809 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44689 BRD-K27351809 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44912 BRD-K27351809 ASC 10 uM 24 h 0.0 0.0 0.0 -0.18 -0.6 0.0
45216 BRD-K27351809 HEPG2 10 uM 6 h -0.22 -0.92 0.06 0.0 0.0 0.0
45482 BRD-K27351809 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45799 BRD-K27351809 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46031 BRD-K27351809 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46347 BRD-K27351809 PHH 10 uM 24 h -0.34 -1.42 1.43 0.0 0.0 0.0
46665 BRD-K27351809 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).