CMap Candidate Details

Structure:
CMap ID: C01106
Pert ID: BRD-A45140972
Compound Name: meclocycline
Targets: --
MoA: --
SMILES: CN(C)[C@H]1[C@@H]2[C@@H](O)C3C(C(=O)c4c(O)ccc(Cl)c4C3=C)C(=O)[C@]2(O)C(=O)C(C(=O)N)C1=O
InchiKey: YKYBWGJKLYMCFI-LOXSQDDVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1499 BRD-A45140972 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1827 BRD-A45140972 HCC515 10 uM 24 h 0.0 0.0 0.0 0.26 0.9 0.22
2533 BRD-A45140972 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41885 BRD-A45140972 A549 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.27
42210 BRD-A45140972 ASC 10 uM 24 h -0.29 -1.19 0.55 0.0 0.0 0.0
42553 BRD-A45140972 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.27 0.95 0.31
42860 BRD-A45140972 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43411 BRD-A45140972 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43721 BRD-A45140972 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44011 BRD-A45140972 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51565 BRD-A45140972 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.25
51783 BRD-A45140972 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).