CMap Candidate Details

Structure:
CMap ID: C01107
Pert ID: BRD-A45153512
Compound Name: bimatoprost
Targets: PTGFR
MoA: Prostanoid receptor agonist
SMILES: CCNC(=O)CCCC=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1C=CC(O)CCc1ccccc1
InchiKey: AQOKCDNYWBIDND-GCYMYIANSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125585 BRD-A45153512 A375 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125614 BRD-A45153512 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125654 BRD-A45153512 HEK293 0.37 uM 24 h 0.3 1.26 0.56 -0.29 -0.96 0.44
125737 BRD-A45153512 HUVEC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
125853 BRD-A45153512 MDAMB231 0.125 uM 24 h 0.25 1.03 0.14 0.0 0.0 0.0
125876 BRD-A45153512 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125935 BRD-A45153512 YAPC 0.125 uM 24 h 0.27 1.11 0.25 0.0 0.0 0.0
133701 BRD-A45153512 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133769 BRD-A45153512 HELA 0.74 uM 24 h 0.33 1.36 0.97 0.21 0.75 0.04
133801 BRD-A45153512 HT29 0.01 uM 24 h -0.23 -0.97 0.11 0.0 0.0 0.0
133827 BRD-A45153512 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.37 1.32 1.71
133859 BRD-A45153512 MCF10A 0.08 uM 24 h -0.25 -1.05 0.23 0.0 0.0 0.0
133885 BRD-A45153512 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133981 BRD-A45153512 THP1 0.74 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.58
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).