CMap Candidate Details

Structure:
CMap ID: C11074
Pert ID: BRD-K27450477
Compound Name: EHNA
Targets: ADA; PDE2A
MoA: Adenosine deaminase inhibitor
SMILES: CCCCCC[C@@H]([C@@H](C)O)n1cnc2c(N)ncnc12
InchiKey: IOSAAWHGJUZBOG-MNOVXSKESA-N
Compound Aliases: ehna

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4088 BRD-K27450477 HA1E 10 uM 24 h 0.25 1.03 0.13 0.32 1.13 0.82
4400 BRD-K27450477 HCC515 10 uM 24 h 0.23 0.94 0.06 -0.32 -1.09 0.81
4667 BRD-K27450477 PC3 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.23 1.28
5062 BRD-K27450477 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39108 BRD-K27450477 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39311 BRD-K27450477 A549 10 uM 24 h 0.0 0.0 0.0 0.39 1.39 2.17
39655 BRD-K27450477 ASC 10 uM 24 h -0.24 -0.98 0.13 -0.41 -1.36 2.02
39971 BRD-K27450477 HEPG2 10 uM 6 h -0.23 -0.96 0.1 -0.33 -1.11 0.92
40248 BRD-K27450477 HT29 10 uM 6 h 0.21 0.89 0.02 0.0 0.0 0.0
40459 BRD-K27450477 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.44 -1.48 15.35
41077 BRD-K27450477 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41409 BRD-K27450477 SKB 10 uM 24 h 0.0 0.0 0.0 0.21 0.75 0.04
98878 BRD-K27450477 NEU 10 uM 24 h 0.23 0.96 0.08 0.3 1.06 0.58
99789 BRD-K27450477 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).