CMap Candidate Details

Structure:
CMap ID: C01109
Pert ID: BRD-A45333398
Compound Name: periplocymarin
Targets: --
MoA: --
SMILES: CO[C@@H]1C[C@H](O[C@H]2CC[C@]3(C)C4CC[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C6=CC(=O)OC6)O[C@H](C)[C@@H]1O
InchiKey: XRWQBDJPMXRDOQ-IDULJFIXSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6645 BRD-A45333398 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7075 BRD-A45333398 A549 10 uM 6 h 0.0 0.0 0.0 -0.53 -1.78 15.65
7229 BRD-A45333398 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.16 1.11
7541 BRD-A45333398 HCC515 10 uM 6 h 0.25 1.03 0.13 -0.5 -1.7 15.65
7770 BRD-A45333398 HT29 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.93
8252 BRD-A45333398 MCF??7.00 10 uM 6 h -0.2 -0.83 0.0 -0.37 -1.24 1.3
8447 BRD-A45333398 PC3 10 uM 6 h 0.0 0.0 0.0 -0.53 -1.77 15.65
8582 BRD-A45333398 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).