CMap Candidate Details

Structure:
CMap ID: C01111
Pert ID: BRD-A45498368
Compound Name: WYE-125132
Targets: MTOR
MoA: MTOR inhibitor
SMILES: CNC(=O)Nc1ccc(cc1)-c1nc(N2CC3CCC(C2)O3)c2cnn(C3CCC4(CC3)OCCO4)c2n1
InchiKey: QLHHRYZMBGPBJG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33572 BRD-A45498368 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33879 BRD-A45498368 A549 10 uM 6 h -0.29 -1.19 0.53 0.0 0.0 0.0
33992 BRD-A45498368 ASC 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.66 0.01
34505 BRD-A45498368 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.75
35513 BRD-A45498368 NEU 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.79
35686 BRD-A45498368 NPC 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
36444 BRD-A45498368 SKB 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.86 0.21
36930 BRD-A45498368 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.8 0.12
91566 BRD-A45498368 HS578T 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91678 BRD-A45498368 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92475 BRD-A45498368 BT20 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92509 BRD-A45498368 HA1E 10 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
92542 BRD-A45498368 HME1 1.11 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.04
92698 BRD-A45498368 LNCAP 10 uM 3 h 0.0 0.0 0.0 -0.39 -1.31 1.7
92745 BRD-A45498368 MCF10A 0.04 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92853 BRD-A45498368 SKBR3 10 uM 3 h 0.21 0.89 0.02 -0.32 -1.07 0.76
96014 BRD-A45498368 PHH 3.33 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.74
119658 BRD-A45498368 HEPG2 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.05
119696 BRD-A45498368 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119743 BRD-A45498368 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 -0.17 -0.57 0.0
119786 BRD-A45498368 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119820 BRD-A45498368 PC3 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.14
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).