CMap Candidate Details

Structure:
CMap ID: C01118
Pert ID: BRD-A45664787
Compound Name: iloprost
Targets: PTGER1; PTGER2; PTGIR
MoA: Prostanoid receptor agonist; Platelet aggregation inhibitor
SMILES: CC#CCC(C)[C@H](O)C=C[C@H]1[C@H](O)C[C@@H]2CC(C[C@H]12)=C/CCCC(O)=O
InchiKey: HIFJCPQKFCZDDL-ACWOEMLNSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1000 BRD-A45664787 CD34 10 uM 6 h -0.34 -1.43 1.43 -0.45 -1.51 15.35
1060 BRD-A45664787 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1120 BRD-A45664787 U937 0.37 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
29729 BRD-A45664787 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
30303 BRD-A45664787 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30631 BRD-A45664787 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
30914 BRD-A45664787 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31209 BRD-A45664787 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31712 BRD-A45664787 HT29 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.83 0.17
31806 BRD-A45664787 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32297 BRD-A45664787 NPC 10 uM 24 h -0.27 -1.11 0.37 0.0 0.0 0.0
32891 BRD-A45664787 SKB 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.73
33206 BRD-A45664787 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.78
91208 BRD-A45664787 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
96084 BRD-A45664787 A549 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).