CMap Candidate Details

Structure:
CMap ID: C11235
Pert ID: BRD-K27955832
Compound Name: lomeguatrib
Targets: MGMT
MoA: AGT inhibitor
SMILES: Nc1nc(OCc2cc(Br)cs2)c2[nH]cnc2n1
InchiKey: JUJPKFNFCWJBCX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
118495 BRD-K27955832 HCC515 10 uM 24 h 0.29 1.21 0.46 0.0 0.0 0.0
118541 BRD-K27955832 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.21 0.74 0.04
118581 BRD-K27955832 HT29 10 uM 24 h 0.25 1.05 0.16 0.28 0.99 0.39
118618 BRD-K27955832 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119941 BRD-K27955832 A375 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.21
119983 BRD-K27955832 A549 0.04 uM 24 h 0.21 0.88 0.02 0.0 0.0 0.0
120022 BRD-K27955832 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120070 BRD-K27955832 HELA 10 uM 3 h 0.0 0.0 0.0 -0.31 -1.06 0.73
120180 BRD-K27955832 PC3 10 uM 24 h -0.18 -0.76 0.0 0.0 0.0 0.0
128868 BRD-K27955832 YAPC 0.08 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).