CMap Candidate Details

Structure:
CMap ID: C01125
Pert ID: BRD-A46335897
Compound Name: promethazine
Targets: HRH1
MoA: Histamine receptor antagonist
SMILES: CC(CN1c2ccccc2Sc2ccccc12)N(C)C
InchiKey: PWWVAXIEGOYWEE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8876 BRD-A46335897 A375 6.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9145 BRD-A46335897 A549 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9913 BRD-A46335897 HA1E 6.66 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.24
10291 BRD-A46335897 HCC515 6.66 uM 6 h 0.0 0.0 0.0 -0.22 -0.75 0.06
10907 BRD-A46335897 HT29 6.66 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.02
11166 BRD-A46335897 MCF??7.00 6.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11344 BRD-A46335897 NCIH2073 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11916 BRD-A46335897 NCIH596 6.66 uM 6 h 0.25 1.05 0.16 0.23 0.81 0.09
12480 BRD-A46335897 PC3 6.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12668 BRD-A46335897 SW480 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13150 BRD-A46335897 U937 6.66 uM 6 h 0.0 0.0 0.0 -0.31 -1.03 0.62
13537 BRD-A46335897 VCAP 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
52790 BRD-A46335897 HEPG2 40 uM 24 h 0.17 0.71 0.0 0.34 1.19 1.03
53277 BRD-A46335897 MCF10A 100 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90978 BRD-A46335897 HUH7 12 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).