CMap Candidate Details

Structure:
CMap ID: C11262
Pert ID: BRD-K28029915
Compound Name: dolasetron
Targets: HTR3A
MoA: Serotonin receptor antagonist
SMILES: O=C(O[C@H]1C[C@H]2C[C@H]3C[C@@H](C1)N2CC3=O)c1c[nH]c2ccccc12
InchiKey: UKTAZPQNNNJVKR-YXSUXZIUSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
21989 BRD-K28029915 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22269 BRD-K28029915 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22460 BRD-K28029915 HA1E 10 uM 6 h 0.3 1.24 0.53 0.0 0.0 0.0
22730 BRD-K28029915 HCC515 10 uM 6 h 0.28 1.16 0.35 0.0 0.0 0.0
23017 BRD-K28029915 HEPG2 10 uM 6 h -0.31 -1.28 0.74 -0.43 -1.46 15.35
23322 BRD-K28029915 HT29 10 uM 6 h 0.0 0.0 0.0 0.29 1.02 0.49
23836 BRD-K28029915 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24294 BRD-K28029915 VCAP 10 uM 6 h -0.25 -1.03 0.19 -0.36 -1.22 1.25
52143 BRD-K28029915 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.16 1.11
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).