CMap Candidate Details

Structure:
CMap ID: C11295
Pert ID: BRD-K28115081
Compound Name: apafant
Targets: PTAFR
MoA: Platelet activating factor receptor antagonist
SMILES: Cc1nnc2CN=C(c3cc(CCC(=O)N4CCOCC4)sc3-n12)c1ccccc1Cl
InchiKey: JGPJQFOROWSRRS-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4402 BRD-K28115081 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
4913 BRD-K28115081 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
39656 BRD-K28115081 ASC 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
39972 BRD-K28115081 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.2 1.16
40776 BRD-K28115081 NEU 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.72
41078 BRD-K28115081 NPC 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.06
41410 BRD-K28115081 SKB 10 uM 24 h -0.26 -1.07 0.27 0.25 0.88 0.18
99794 BRD-K28115081 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
121899 BRD-K28115081 A375 0.125 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.43
121919 BRD-K28115081 A549 10 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
121984 BRD-K28115081 HELA 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.11
122012 BRD-K28115081 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.33 1.17 0.95
122056 BRD-K28115081 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122110 BRD-K28115081 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.62
122143 BRD-K28115081 MDAMB231 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
130234 BRD-K28115081 HA1E 2.22 uM 24 h 0.21 0.88 0.01 -0.27 -0.92 0.32
130260 BRD-K28115081 HEK293 0.74 uM 24 h -0.25 -1.06 0.25 -0.28 -0.94 0.36
130357 BRD-K28115081 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130405 BRD-K28115081 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130480 BRD-K28115081 PC3 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130497 BRD-K28115081 THP1 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130528 BRD-K28115081 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).