CMap Candidate Details

Structure:
CMap ID: C01130
Pert ID: BRD-A46747628
Compound Name: ouabain
Targets: ATP1A1
MoA: ATPase inhibitor
SMILES: CC1OC(OC2CC(O)C3(CO)C4C(O)CC5(C)C(CCC5(O)C4CCC3(O)C2)C6=CC(=O)OC6)C(O)C(O)C1O
InchiKey: LPMXVESGRSUGHW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5402 BRD-A46747628 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5728 BRD-A46747628 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6244 BRD-A46747628 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6467 BRD-A46747628 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44247 BRD-A46747628 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44482 BRD-A46747628 A549 10 uM 24 h 0.0 0.0 0.0 -0.48 -1.62 15.65
44769 BRD-A46747628 ASC 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 0.98
45089 BRD-A46747628 HEPG2 10 uM 6 h -0.26 -1.07 0.28 -0.54 -1.81 15.65
45364 BRD-A46747628 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45745 BRD-A46747628 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45888 BRD-A46747628 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46204 BRD-A46747628 PHH 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.13 0.97
46519 BRD-A46747628 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).