CMap Candidate Details

Structure:
CMap ID: C11308
Pert ID: BRD-K28143534
Compound Name: cyproheptadine
Targets: HRH1
MoA: Histamine receptor antagonist
SMILES: CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12
InchiKey: JJCFRYNCJDLXIK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
22270 BRD-K28143534 A549 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.05 0.7
22731 BRD-K28143534 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.22 1.25
23018 BRD-K28143534 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.2 1.17
23323 BRD-K28143534 HT29 10 uM 6 h 0.25 1.05 0.16 0.0 0.0 0.0
23561 BRD-K28143534 MCF??7.00 10 uM 24 h 0.32 1.32 0.82 0.0 0.0 0.0
24139 BRD-K28143534 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91495 BRD-K28143534 HUH7 12 uM 72 h -0.3 -1.24 0.67 0.31 1.09 0.67
96017 BRD-K28143534 PHH 3.33 uM 24 h -0.25 -1.06 0.25 -0.24 -0.79 0.11
99795 BRD-K28143534 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
119942 BRD-K28143534 A375 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
120023 BRD-K28143534 HA1E 10 uM 24 h 0.21 0.86 0.01 -0.32 -1.09 0.82
120181 BRD-K28143534 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120213 BRD-K28143534 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128828 BRD-K28143534 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).