CMap Candidate Details

Structure:
CMap ID: C11316
Pert ID: BRD-K28168037
Compound Name: fenretinide
Targets: RARA
MoA: Apoptosis stimulant; Retinoid receptor agonist
SMILES: CC(=CC=CC(=CC(=O)Nc1ccc(O)cc1)C)C=CC2=C(C)CCCC2(C)C
InchiKey: AKJHMTWEGVYYSE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4089 BRD-K28168037 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4404 BRD-K28168037 HCC515 10 uM 24 h 0.0 0.0 0.0 0.21 0.75 0.04
4669 BRD-K28168037 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4914 BRD-K28168037 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37137 BRD-K28168037 A375 10 uM 6 h 0.0 0.0 0.0 0.25 0.89 0.19
37277 BRD-K28168037 A549 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.26 1.35
37625 BRD-K28168037 ASC 10 uM 24 h 0.0 0.0 0.0 -0.59 -1.98 15.65
37886 BRD-K28168037 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.2 0.7 0.01
38069 BRD-K28168037 HT29 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.03 0.65
38701 BRD-K28168037 PHH 10 uM 24 h 0.27 1.11 0.25 -0.28 -0.95 0.4
38934 BRD-K28168037 SKB 10 uM 24 h 0.25 1.04 0.15 -0.4 -1.33 1.82
97782 BRD-K28168037 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.32 1.71
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).