CMap Candidate Details

Structure:
CMap ID: C11319
Pert ID: BRD-K28178212
Compound Name: GW-441756
Targets: NTRK1
MoA: Growth factor receptor inhibitor
SMILES: Cn1cc(C=C2C(=O)Nc3cccnc23)c2ccccc12
InchiKey: NXNQLECPAXXYTR-UKTHLTGXSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33706 BRD-K28178212 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33897 BRD-K28178212 A549 10 uM 6 h 0.0 0.0 0.0 0.26 0.92 0.25
34073 BRD-K28178212 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34339 BRD-K28178212 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34589 BRD-K28178212 HCC515 10 uM 6 h -0.21 -0.89 0.03 0.0 0.0 0.0
34859 BRD-K28178212 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.95 0.41
35121 BRD-K28178212 HT29 10 uM 6 h 0.0 0.0 0.0 0.29 1.01 0.46
35309 BRD-K28178212 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35758 BRD-K28178212 NPC 10 uM 24 h 0.0 0.0 0.0 -0.47 -1.57 15.65
36071 BRD-K28178212 PC3 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.05 0.7
36235 BRD-K28178212 PHH 10 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.22
36529 BRD-K28178212 SKB 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
36798 BRD-K28178212 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).