CMap Candidate Details

Structure:
CMap ID: C01134
Pert ID: BRD-A47065382
Compound Name: huperzine-a
Targets: ACHE
MoA: Glutamate receptor antagonist; Acetylcholinesterase inhibitor
SMILES: C/C=C/1C2Cc3[nH]c(=O)ccc3C1(N)CC(=C2)C
InchiKey: ZRJBHWIHUMBLCN-QDEBKDIKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6647 BRD-A47065382 A375 10 uM 24 h 0.0 0.0 0.0 0.35 1.24 1.24
7077 BRD-A47065382 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7231 BRD-A47065382 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7544 BRD-A47065382 HCC515 10 uM 6 h 0.23 0.96 0.08 -0.32 -1.07 0.75
7771 BRD-A47065382 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8233 BRD-A47065382 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8306 BRD-A47065382 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8758 BRD-A47065382 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
100180 BRD-A47065382 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).