CMap Candidate Details

Structure:
CMap ID: C11357
Pert ID: BRD-K28307902
Compound Name: flutamide
Targets: AR
MoA: Androgen receptor antagonist
SMILES: CC(C)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O
InchiKey: MKXKFYHWDHIYRV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5765 BRD-K28307902 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9398 BRD-K28307902 AGS 30 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9709 BRD-K28307902 H1299 30 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10493 BRD-K28307902 HCT116 30 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10767 BRD-K28307902 HEPG2 30 uM 6 h -0.26 -1.08 0.3 -0.38 -1.28 1.45
11460 BRD-K28307902 NCIH2073 30 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11743 BRD-K28307902 NCIH508 30 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.38
12024 BRD-K28307902 NCIH596 30 uM 6 h -0.25 -1.03 0.19 0.0 0.0 0.0
12771 BRD-K28307902 SW480 30 uM 6 h 0.29 1.19 0.42 -0.34 -1.14 1.05
39658 BRD-K28307902 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40778 BRD-K28307902 NEU 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
41080 BRD-K28307902 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41412 BRD-K28307902 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53304 BRD-K28307902 MCF10A 100 uM 24 h 0.0 0.0 0.0 -0.39 -1.3 1.57
90399 BRD-K28307902 VCAP 3.33 uM 24 h 0.26 1.1 0.24 0.0 0.0 0.0
91361 BRD-K28307902 HUH7 12 uM 72 h 0.0 0.0 0.0 -0.35 -1.17 1.11
99798 BRD-K28307902 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
119880 BRD-K28307902 A549 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.33
121949 BRD-K28307902 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121975 BRD-K28307902 HELA 10 uM 24 h -0.21 -0.89 0.04 -0.29 -0.99 0.51
122032 BRD-K28307902 HUVEC 1.11 uM 24 h -0.36 -1.49 1.43 0.31 1.09 0.67
122132 BRD-K28307902 MDAMB231 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130179 BRD-K28307902 A375 0.03 uM 24 h 0.28 1.15 0.32 -0.38 -1.27 1.44
130216 BRD-K28307902 HA1E 0.25 uM 24 h 0.21 0.86 0.01 -0.29 -0.99 0.5
130311 BRD-K28307902 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130334 BRD-K28307902 JURKAT 0.74 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
130426 BRD-K28307902 MCF??7.00 0.25 uM 24 h -0.23 -0.95 0.09 0.27 0.96 0.34
130473 BRD-K28307902 PC3 0.74 uM 24 h 0.23 0.97 0.08 -0.32 -1.07 0.75
130489 BRD-K28307902 THP1 0.03 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.06
130514 BRD-K28307902 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).