CMap Candidate Details

Structure:
CMap ID: C11385
Pert ID: BRD-K28392481
Compound Name: AZD-4547
Targets: --
MoA: --
SMILES: COc1cc(CCc2cc(NC(=O)c3ccc(cc3)N3C[C@H](C)N[C@H](C)C3)n[nH]2)cc(OC)c1
InchiKey: VRQMAABPASPXMW-HDICACEKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
92926 BRD-K28392481 ASC 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.16
92988 BRD-K28392481 CD34 10 uM 24 h 0.31 1.27 0.58 0.0 0.0 0.0
93076 BRD-K28392481 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93165 BRD-K28392481 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93213 BRD-K28392481 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93270 BRD-K28392481 JURKAT 0.12 uM 24 h -0.29 -1.22 0.61 -0.28 -0.93 0.34
93415 BRD-K28392481 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93478 BRD-K28392481 SKL 10 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.34
93538 BRD-K28392481 THP1 3.33 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.1
121885 BRD-K28392481 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121914 BRD-K28392481 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122000 BRD-K28392481 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122086 BRD-K28392481 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122100 BRD-K28392481 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122157 BRD-K28392481 PC3 10 uM 24 h -0.24 -1.01 0.16 0.0 0.0 0.0
122210 BRD-K28392481 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130217 BRD-K28392481 HA1E 2.22 uM 24 h 0.26 1.09 0.22 0.0 0.0 0.0
130278 BRD-K28392481 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.37 1.32 1.7
130442 BRD-K28392481 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.14
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).