CMap Candidate Details

Structure:
CMap ID: C11409
Pert ID: BRD-K28453807
Compound Name: nitrocaramiphen
Targets: CHRM1
MoA: Cholinergic receptor antagonist
SMILES: CCN(CC)CCOC(=O)C1(CCCC1)c1ccc(cc1)[N+]([O-])=O
InchiKey: NSHMVLOWOAQFTP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4090 BRD-K28453807 HA1E 10 uM 24 h 0.24 1.0 0.1 -0.29 -0.98 0.48
4406 BRD-K28453807 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4670 BRD-K28453807 PC3 10 uM 24 h 0.25 1.04 0.14 0.0 0.0 0.0
4915 BRD-K28453807 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39110 BRD-K28453807 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39437 BRD-K28453807 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39659 BRD-K28453807 ASC 10 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.31
39974 BRD-K28453807 HEPG2 10 uM 6 h -0.29 -1.21 0.59 0.0 0.0 0.0
40250 BRD-K28453807 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40604 BRD-K28453807 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40779 BRD-K28453807 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41081 BRD-K28453807 NPC 10 uM 24 h 0.27 1.13 0.29 0.0 0.0 0.0
41413 BRD-K28453807 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).