CMap Candidate Details

Structure:
CMap ID: C11411
Pert ID: BRD-K28456624
Compound Name: seocalcitol
Targets: VDR
MoA: Vitamin D receptor agonist
SMILES: CCC(O)(CC)C=CC=C[C@@H](C)[C@H]1CC[C@@H]2[C@]1(C)CCCC2=C/C=C1/C[C@@H](O)C[C@H](O)C1=C
InchiKey: LVLLALCJVJNGQQ-SEODYNFXSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95325 BRD-K28456624 A549 10 uM 48 h 0.22 0.9 0.02 0.32 1.12 0.79
95408 BRD-K28456624 U2OS 10 uM 24 h 0.25 1.04 0.15 0.0 0.0 0.0
122002 BRD-K28456624 HT29 0.04 uM 24 h 0.26 1.09 0.23 0.0 0.0 0.0
122038 BRD-K28456624 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
122103 BRD-K28456624 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122159 BRD-K28456624 PC3 0.37 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
122185 BRD-K28456624 THP1 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130181 BRD-K28456624 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130219 BRD-K28456624 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130251 BRD-K28456624 HEK293 0.03 uM 24 h 0.24 1.01 0.11 0.0 0.0 0.0
130281 BRD-K28456624 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130340 BRD-K28456624 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130390 BRD-K28456624 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130445 BRD-K28456624 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130516 BRD-K28456624 YAPC 0.08 uM 24 h 0.0 0.0 0.0 -0.41 -1.38 2.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).