CMap Candidate Details

Structure:
CMap ID: C01147
Pert ID: BRD-A47494775
Compound Name: dipivefrine
Targets: ADRA1A
MoA: Adrenergic receptor agonist
SMILES: CNCC(O)c1ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c1
InchiKey: OCUJLLGVOUDECM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6649 BRD-A47494775 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6936 BRD-A47494775 A549 10 uM 24 h -0.28 -1.16 0.45 0.0 0.0 0.0
7232 BRD-A47494775 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7546 BRD-A47494775 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7773 BRD-A47494775 HT29 10 uM 24 h -0.25 -1.05 0.24 -0.25 -0.83 0.16
8759 BRD-A47494775 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.13 0.97
51675 BRD-A47494775 MCF??7.00 10 uM 6 h 0.26 1.08 0.22 0.0 0.0 0.0
51784 BRD-A47494775 PC3 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.96
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).