CMap Candidate Details

Structure:
CMap ID: C11495
Pert ID: BRD-K28731095
Compound Name: calcitriol
Targets: VDR
MoA: Vitamin D receptor agonist
SMILES: C[C@H](CCCC(C)(C)O)[C@@H]1CC[C@@H]2[C@]1(C)CCCC2=C/C=C1/C[C@@H](O)C[C@H](O)C1=C
InchiKey: GMRQFYUYWCNGIN-WEARQXOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90626 BRD-K28731095 HCT116 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90686 BRD-K28731095 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95523 BRD-K28731095 A549 4 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
95684 BRD-K28731095 U2OS 4 uM 48 h 0.29 1.23 0.5 -0.34 -1.15 1.06
97985 BRD-K28731095 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
98018 BRD-K28731095 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98061 BRD-K28731095 P1A82 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119944 BRD-K28731095 A375 3.33 uM 24 h -0.3 -1.24 0.64 -0.22 -0.75 0.06
120050 BRD-K28731095 HELA 1.11 uM 24 h -0.28 -1.15 0.43 0.0 0.0 0.0
120103 BRD-K28731095 HT29 3.33 uM 24 h -0.24 -1.02 0.18 -0.37 -1.23 1.28
120184 BRD-K28731095 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120216 BRD-K28731095 YAPC 3.33 uM 24 h 0.0 0.0 0.0 -0.37 -1.23 1.28
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).