CMap Candidate Details

Structure:
CMap ID: C01150
Pert ID: BRD-A47598013
Compound Name: citalopram
Targets: SLC6A4
MoA: Serotonin reuptake inhibitor
SMILES: CN(C)CCCC1(OCc2cc(ccc12)C#N)c1ccc(F)cc1
InchiKey: WSEQXVZVJXJVFP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1448 BRD-A47598013 NPC 6.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7548 BRD-A47598013 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
19387 BRD-A47598013 A549 10 uM 6 h 0.23 0.95 0.06 -0.37 -1.24 1.35
19552 BRD-A47598013 HA1E 10 uM 6 h 0.16 0.68 0.0 0.0 0.0 0.0
20202 BRD-A47598013 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20835 BRD-A47598013 MCF??7.00 10 uM 24 h 0.21 0.86 0.01 0.25 0.9 0.21
25297 BRD-A47598013 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91467 BRD-A47598013 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
100183 BRD-A47598013 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
124568 BRD-A47598013 A375 10 uM 24 h 0.0 0.0 0.0 0.36 1.28 1.42
124679 BRD-A47598013 HT29 0.04 uM 24 h 0.28 1.17 0.37 0.0 0.0 0.0
124780 BRD-A47598013 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124825 BRD-A47598013 PC3 0.04 uM 24 h 0.25 1.05 0.17 0.25 0.89 0.2
124869 BRD-A47598013 THP1 3.33 uM 24 h -0.28 -1.18 0.5 0.0 0.0 0.0
132739 BRD-A47598013 HEK293 0.01 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.19
132780 BRD-A47598013 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.43 1.52 2.29
132825 BRD-A47598013 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132857 BRD-A47598013 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132942 BRD-A47598013 YAPC 0.25 uM 24 h -0.21 -0.86 0.02 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).