CMap Candidate Details
Structure:
| CMap ID: | C11505 |
| Pert ID: | BRD-K28761891 |
| Compound Name: | ramelteon |
| Targets: | MTNR1A; MTNR1B |
| MoA: | Melatonin receptor agonist |
| SMILES: | CCC(=O)NCC[C@@H]1CCc2ccc3OCCc3c12 |
| InchiKey: | YLXDSYKOBKBWJQ-LBPRGKRZSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 119945 | BRD-K28761891 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.14 | 1.02 |
| 119987 | BRD-K28761891 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.25 | 0.89 | 0.2 |
| 120025 | BRD-K28761891 | HA1E | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120051 | BRD-K28761891 | HELA | 0.04 uM | 24 h | 0.2 | 0.83 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120104 | BRD-K28761891 | HT29 | 0.125 uM | 24 h | -0.24 | -1.02 | 0.18 | 0.0 | 0.0 | 0.0 |
| 120146 | BRD-K28761891 | MCF??7.00 | 3.33 uM | 24 h | 0.27 | 1.14 | 0.31 | 0.0 | 0.0 | 0.0 |
| 120185 | BRD-K28761891 | PC3 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.29 | 1.04 | 0.56 |
| 128870 | BRD-K28761891 | YAPC | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |