CMap Candidate Details

Structure:
CMap ID: C11518
Pert ID: BRD-K28806945
Compound Name: L-750667
Targets: DRD4
MoA: Dopamine receptor antagonist
SMILES: Ic1ccc(cc1)N2CCN(Cc3c[nH]c4ncccc34)CC2
InchiKey: OOEUHRGMLFVKQO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1576 BRD-K28806945 HA1E 10 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
1912 BRD-K28806945 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2305 BRD-K28806945 PC3 10 uM 24 h -0.17 -0.72 0.0 0.28 1.01 0.44
2792 BRD-K28806945 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41758 BRD-K28806945 A375 10 uM 6 h -0.27 -1.13 0.4 -0.21 -0.71 0.03
42087 BRD-K28806945 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42344 BRD-K28806945 ASC 10 uM 24 h 0.0 0.0 0.0 0.39 1.39 2.17
42670 BRD-K28806945 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42975 BRD-K28806945 HT29 10 uM 6 h 0.0 0.0 0.0 0.2 0.69 0.01
43180 BRD-K28806945 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43536 BRD-K28806945 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43833 BRD-K28806945 PHH 10 uM 24 h 0.31 1.3 0.69 -0.3 -1.02 0.6
44103 BRD-K28806945 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99804 BRD-K28806945 U2OS 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.96 0.43
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).