CMap Candidate Details

Structure:
CMap ID: C11538
Pert ID: BRD-K28863208
Compound Name: PNU-282987
Targets: CHRNA7
MoA: Cholinergic receptor agonist
SMILES: Clc1ccc(cc1)C(=O)N[C@H]1CN2CCC1CC2
InchiKey: WECKJONDRAUFDD-ZDUSSCGKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4211 BRD-K28863208 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4558 BRD-K28863208 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4794 BRD-K28863208 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5065 BRD-K28863208 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.32 1.71
37139 BRD-K28863208 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37375 BRD-K28863208 A549 10 uM 6 h 0.18 0.74 0.0 0.0 0.0 0.0
37627 BRD-K28863208 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37888 BRD-K28863208 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38070 BRD-K28863208 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38244 BRD-K28863208 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38454 BRD-K28863208 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38703 BRD-K28863208 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99805 BRD-K28863208 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).